ORAL DELIVERY

Conventional lipids, such as phospholipids, are sensitive to the harsh conditions of the gastrointestinal (GI) tract. They offer limited protection to drug substances and often fail to ensure effective delivery. As a result, conventional liposomes and lipid nanoparticles are typically administered via parenteral routes.

In contrast, NovoArc’s proprietary lipids and lipid-based formulations offer several key advantages for oral drug delivery:

  • Protection against gastrointestinal hydrolysis, enzymatic lipolysis, and particle agglomeration

  • Extended shelf life at room temperature

  • Enhanced bioavailability following oral administration

Therefore, NovoArc lipids can be used to deliver a variety of drug substances directly to the intestine. They have been tested in animal studies, demonstrating high tolerability after oral administration.

These properties make NovoArc’s lipid technology a strong platform for enabling the oral delivery of sensitive or poorly bioavailable compounds.

 

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